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KMID : 0605620170240030129
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Journal of Korean Society of Biological Psychiatry
2017 Volume.24 No. 3 p.129 ~ p.133
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Association between Quality of Life and Symptom Severity in Obsessive-Compulsive Disorder Patients Using EQ-5D
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Kim Sung-Nyen
Moon Woo-Ri
Han Jae-Wook
Lee Jun-Hee
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Abstract
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Objectives : Obsessive-compulsive disorder (OCD) is a disabling psychiatric disorder, and more attention is recently paid on the quality of life (QoL) in OCD patients. The Euro-QoL-5D (EQ-5D) is a widely used self-report to calculate a single score which represents 'health utilities'. The aim of this study was to assess the health-related QoL for patients with OCD using the EQ-5D and to examine the relationship between health-related QoL and symptom severity.
Methods : Seventy-three patients with a Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnosis of OCD were recruited from the outpatient clinic in Seoul National University Hospital. Symptom severity was assessed using the Yale-Brown Obsessive-Compulsive Scale (YBOCS), and QoL was assessed with the EQ-5D-5L questionnaire. Using Korean valuation study, a single score of QoL was calculated.
Results : Most of the OCD patients were relatively young (< 45 years) with the mean YBOCS total score of 19.33. The mean EQ-5D score was 0.71 and significantly correlated with symptom severity (r = -0.483, p < 0.001). 25% of the EQ-5D score was predicted by the YBOCS total score (b = -0.011, p < 0.001) by regression analysis.
Conclusions : OCD patients suffer from lower health-related QoL and QoL significantly decreased as symptom severity increased. The results of the EQ-5D would enable further studies on QoL comparison across medical disease and mental disorders.
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KEYWORD
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Quality of life, EQ-5D, Obsessive-compulsive disorder, Symptom severity
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